ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0017.11-10 | Body Weight Regulation and Insulin Sensitivity | ESPEYB17

11.10. The [beta]3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans

BS Finlin , H Memetimin , B Zhu , AL Confides , HJ Vekaria , RH El Khouli , ZR Johnson , PM Westgate , J Chen , AJ Morris , PG Sullivan , EE Dupont-Versteegden , PA Kern

To read the full abstract: J Clin Invest. 2020;130(5):2319–2331.This clinical study assessed the effect of the β3-adrenergic agonist mirabegron on glucose homeostasis in obese individuals.Chronic activation of β3-receptors in mice leads to the appearance of brown-like (e.g. ‘beige’) adipocytes in white adipose tissue, a process referred to as ...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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